2025 March Madness Odds: Who Is the Favorite for the National Championship Post-Selection Sunday?

March Madness 2025 is officially underway, and after a thrilling SEC tournament, Florida has emerged as the new favorite to win the national championship. Following their impressive victory over Tennessee, the Gators have solidified their position as the top contender, with +350 odds at BetMGM to win it all. Florida, now holding the No. 1 seed in the West region, enters the tournament with a 30-4 record, boasting a remarkable 12-1 streak over their last 13 games.

The Gators‘ remarkable performance in the SEC tournament, where they defeated Tennessee for the title, has propelled them to the forefront of March Madness 2025 betting odds. Their only four losses this season came at the hands of teams that also made the NCAA tournament-Kentucky, Tennessee, Georgia, and Missouri. With their solid track record, they have emerged as a strong favorite to capture the national title.

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Florida leads the pack

However, Florida is not the only team to watch closely this year. Duke, just behind Florida in the odds at +360, is another powerhouse team that has captured attention. The Blue Devils dominated the ACC and secured the ACC tournament title, despite the injury to Cooper Flagg, who is expected to be fully ready for tournament play. With Flagg’s return, Duke’s chances to go deep in the tournament have only strengthened.

Auburn, the No. 1 overall seed, is currently listed at +400 to win the title, though their recent form, losing three of their last four games, raises some concerns. The Tigers have a tough road ahead, starting with their matchups in Lexington, Kentucky, where they could potentially face a strong Louisville team.

Other notable contenders

Houston, ranked No. 1 in the Midwest, rounds out the top contenders with +600 odds. The Cougars dominated the Big 12, winning both the regular season and tournament titles, and are ready to make a serious push for the championship. The next tier of favorites includes Alabama (+1200) and Tennessee (+1400), both of whom possess top-tier defenses and have the potential to make a deep run.

There are also a few surprises in the odds this year. UConn and Gonzaga, both No. 8 seeds, are given +5000 odds to win it all, despite potentially tough matchups in the second round. UConn is aiming for a third consecutive national title, and their pedigree has made them a sleeper pick in this year’s tournament.

With an exciting tournament ahead, all eyes are on the Gators as they lead the race, but the competition remains fierce with several powerhouse teams closely behind.

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